Cadalmin GAe (Capsules)  

The term arthritis literally means “joint inflammation,” but it is generally used to refer to a family of more than 100 different conditions that affect the joints and may also affect muscles and other tissues. The most common form of arthritis degenerative arthritis or osteoarthritis results from the breakdown of the tissue inside the joints. It affects more than 20 million people in the U.S. The other form inflammatory arthritis results from swelling in the joints. Rheumatoid arthritis is a common type of inflammatory arthritis.

Osteoarthritis of the knee and non-specific low back pain (NSLBP) are among the most common rheumatic disorders in the Asia-Pacific region. Studies have shown the prevalence of knee osteoarthritis (KOA) to be 7.50%, 10.9% and 13.6% in China. In India and Bangladesh it is reported to be 5.78% and 10.20% respectively. A study in Pakistan has shown that 28.00% of the urban and 25.00% of the rural population have knee osteoarthritis (KOA).
  Mother nature‘s first ever effective and safe research molecule for all kind of joints pain

Product concept:
Concerted research effort by the scientists of CMFRI & Celestial Bio Labs Limited to explore new sources of secondary metabolites from sea weeds led to the design & development of Cadalmin GAe a Nutraceutical to combat inflammatory diseases. This is a natural alternative to synthetic anti-inflammatory drugs for combating Arthritis.

Product Benefits:
Cadalmin GAe Green Algal extract (GAe) contains a unique blend of natural marine bioactive anti-inflammatory ingredients extracted from selected seaweeds or marine macro algae with a patented eco-friendly “green” technology.

Mode of Action:
The active principles in Cadalmin GAe competitively inhibit inflammatory  cycloxygenases and lipoxygenase in an inflammation and oxidative stress reaction, resulting in decreased production of pro-inflammatory prostaglandins and leukotrienes and its activity was found to be superior to some of the synthetic non steroidal anti-inflammatory drugs like aspirin available in the market.

Experimental study:
The mean lethal dose (LD50) of Cadalmin GAe was found to be greater than 4000 mg/kg body weight of the mammalian subjects that indicate the safety of the product. As part of the further safety assessment of the extract, feeding of Cadalmin GAe even at a dose upto 2500 mg/kg body weight did not induce significant change in body weights, hematological indices, histo-pathological, and serum biochemical parameters between the control and treated groups indicating that it has no toxicity to the experimental animals.

Clinical study:
Cadalmin GAe was distributed to more than 400 patients suffering with chronic joint pain and arthritis, and questionnaire and clinical trial-based studies revealed that more than 98% of the respondents were satisfied with the product with about 70-85% relief in joint pain and arthritis. None of the respondents reported any side effects. The diagnostically useful autoantibody termed as Rheumatoid Factors (RFs), which are the most useful prognostic marker for rheumatoid arthritis, significantly reduced from more than 300 IU/ml to less than 20-35 IU/ml within a period of two months of consuming the product.

2 capsules twice a day for three months followed by a, maintenance dose of 1 capsule twice daily OR Please consult the Doctor to prescribe the dosage that best suits your condition.

Side Effects:
It is absolutely safe medicine without any reported side effects.

Patients who are allergic to sea food need to consult the doctor before taking the medicine.

Available in HDPE container of 60 capsules pack.

The information on this page is not intended to be a substitute for professional medical advice. Do not use this information to diagnose or treat your problem without consulting your doctor.

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